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Our NFL betting guide tells you where to bet on NFL Week 1, while providing odds, betting trends, schedule, promo offers, and more

Backing home underdogs like the Colts and Texans offers strong Week 1 value, while Jalen Hurts and the Eagles are primed to cover against the Commanders

Despite missing multiple training camp practices and preseason games in his first offseason with the 49ers, Mike Evans

George Kittle returning to play nearly nine months to the day after tearing his achilles is a remarkable accomplishment. In the 49ers 27-7 victory over

In what was the lowest-scoring game for a Matthew Stafford-led Rams’ offense, Puka Nacua still produced 12.4 PPR. He finished opening week in Australi

The Cardinals expect their first-round running back to play against the Chargers, but there are still questions to answer

Brooks (groin) was in uniform for Friday’s practice, his third straight session, Mike Kaye of ESPN.com reports. Visit RotoWire.com for more analysis on this update.

Myles Garrett recorded zero tackles and zero sacks in his Rams debut, citing a lingering knee injury during the season-opening loss to the 49ers

SportsLine’s advanced model has locked in its Week 1 NFL predictions from 10,000 simulations

A look at what makes this Dolphins team so alarming

The New England Patriots are adding some size to their defensive line. Veteran tackle DaQuan Jones, who is listed at 6-foot-4 and 320 pounds, is set to join the team...

Sanders will serve as the Jets’ kicker this week, Zack Rosenblatt reports Aaron Glenn said Friday. Visit RotoWire.com for more analysis on this update.

A look at some of the less talked about games you should be watching to kick off the 2026 season

Love (ankle) is expected to play Sunday against the Chargers, Josh Weinfuss of ESPN.com reports. Visit RotoWire.com for more analysis on this update.

SportsLine football expert Emory Hunt lines up his best bets for Week 15 of the 2026 CFL season

Buffalo has to buck a recent trend in order to start the season in the win column

My wife and I have been watching the new HBO series Lanterns when we’ve got time. First, it’s an excellent show. Kyle Chandler and Aaron Pierre are the perfect pairing....

[NFL injury updates live] Jump to a team: AFC East:Bills | Dolphins | Patriots (played Wed.) | JetsAFC North: Ravens | Bengals | Browns | SteelersAFC South:Texans | Colts |...

IDP Director Jon Glosser is back with your starts, sits, and streamers for Week 1 of the 2026 fantasy football season. We break down the DL, LB, and DB options...

CBSSports.com and SportsLine break down every single NFL game in Week 1

History shows good teams can survive a short-term QB injury — and Seattle has the roster to do it

Reigning picks champ Jordan Dajani gives his picks for Week 1 of the 2025 NFL season

Five bold predictions to start the NFL season, from Tua Tagovailoa outdoing Rodgers to Josh Allen finally overcoming his Houston woes

Lamar Jackson and Daniel Jones look to bounce back from injury-plagued seasons

Plus, picks for all 16 games as the 2026 season begins

The San Francisco 49ers cruised past the Los Angeles Rams 27–7 in Week 1 on September 11, 2026. 49ers outgained the Rams, 379 total yards to 290.